Wednesday, July 6, 2011
BIO-SYNTHESIS is second to none in its ability to meet our customer's needs, often providing modified DNA with wide variety of selections. BSI offer PNA/DNA chimera synthesis at competitive prices and quick delivery. Bio-Synthesis continued to provide quality DNA products and services for the research community, but it has also become a world leader in providing custom peptide products and services.
A DNA sequence or genetic sequence is a succession of letters representing the primary structure of a real or hypothetical DNA molecule or strand, with the capacity to carry information. The possible letters are A, C, G, and T, representing the four nucleotide subunits of a DNA strand - adenine, cytosine, guanine, thymine bases covalently linked to phospho-backbone. In the typical case, the sequences are printed abutting one another without gaps, as in the sequence AAAGTCTGAC, going from 5' to 3' from left to right. A succession of any number of nucleotides greater than four is liable to be called a sequence.
The concept was to mimic an oligonucleotide binding to double stranded DNA via Hoogsteen base pairing in the major groove. Thus the nucleobases of DNA were retained, but the deoxyribose phosphodiester backbone of DNA was replaced by a pseudo-peptide backbone that according to computer model building was homomorphous with the DNA backbone.
Deoxyribonucleic acid (DNA) is a nucleic acid that contains the genetic instructions used in the development and functioning of all known living organisms and some viruses. The main role of DNA molecules is the long-term storage of information.